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Table 1 Comparison of the functionality of currently available systematic review management software packages

From: Online tools supporting the conduct and reporting of systematic reviews and systematic maps: a case study on CADIMA and review of existing tools

Software name

Ownership

Website

Descriptiona

Intended field(s) of research

Available support

Stages of the SR process supportedb

Web–online

Downloadable

Supports offline working

Supports team of reviewers

Text mining features (for screening, data extraction or synthesis)

Open source

Costc

CADIMA [32]

JKI—Julius Kühn-Institut

https://www.cadima.info/index.php/area/evidenceSynthesisDatabase

“CADIMA supports the conduct of systematic reviews and evidence/systematic maps by the provision of a freely available online tool.”

Any, particularly suitable for Environmental Evidence systematic maps and reviews

Development team is available to provide support or software modifications

Qu, Pi, Du, Sc, Co, Cr, Do

Yes

No

Yes (at data coding stage)

Yes

Text mining capabilities in development

No

Free

Colandr

Conservation International

www.colandrapp.com

“computer-assisted systematic mapping software for evidence synthesis”

Any, particularly suitable for environment and development sectors

Colandr Community website, videos, documentation

Pi, Se, Du, Sc, Co, Sy, Do

Yes

No

No

Yes

Machine learning approaches to assist with article screening and data extraction

Yes

Free

Covidence [33]

Covidence is a non-profit organisation

https://www.covidence.org/

“Covidence is a not-for-profit service working in partnership with Cochrane to improve the production and use of systematic reviews for health and wellbeing.”

Healthcare and medical science, designed for Cochrane reviews

Detailed help documentation and demonstration videos. Contact support available

Du, Sc, Co, Cr

Yes

No

No

Yes

No

No

Range of packages e.g. ‘Single’: $240 USD per year, one review, unlimited reviewers

DistillerSR [34]

Privately held, Evidence Partners

https://www.evidencepartners.com/products/distillersr-systematic-review-software/

“DistillerSR is the world’s most used systematic review software. It was designed from the ground up to give you a better review experience, faster project completion and transparent, audit-ready results.”

Any

8X5 live technical support and detailed user manual with explanatory videos. Support for international character sets

Se (PubMed), Du, Sc, Co, Sy, Do

Yes

No

No

Yes

In develoment. Currently supports keyword highlightingd

No

Range of packages e.g. Student FREE: USD$0 and’Faculty’: USD$75 per month

Early review organizing software (EROS) [35]

Institute of Clinical Effectiveness and Health Policy

http://eros-systematic-review.org/rev-login.php

“EROS is a new web-based software designed specifically to perform the first stages of a systematic review.”

Healthcare and medical science

Email support and a user guide

Sc, Co, Cr

Yes

No

No

Yes

No

No

A donation for development (USD 600 per year for a team of up to four reviewers) is requested for non-Cochrane reviews (Cochrane reviews can use Covidence for free)

EPPI-Reviewer 4 [36]

EPPI-Centre

http://eppi.ioe.ac.uk/CMS/Default.aspx?alias=eppi.ioe.ac.uk/cms/er4&

“EPPI-Reviewer 4 is a multi-user web-based application for managing and analyzing data for use in research synthesis.”

Any

Detailed user manual and developers are available with advice and to make modification where possible

Se, Du, Sc, Co, Cr, Sy, Do

Yes

No

No

Yes

Text mining to assist with identifying relevant studies

No

User fee £10 per user per month, plus shareable review fee £35 per month

Health Assessment Workspace Collaborative (HAWC) [37, 38]

Collaborative initiative

https://hawcproject.org/

“HAWC is a modular, content management system designed to store, display, and synthesize multiple data sources for the purpose of producing human health assessments of chemicals.”

Healthcare and medical science

Online documentation http://hawc.readthedocs.io/en/latest/ and Github repository. Requires knowledge of Python to run and to interpret help documentation

Se, Sc, Co, Cr, Sy, Do

Yes

No

No

Yes

Unavailable

Yes

Free

METAGEAR package for R [39]

Marc J. Lajeunesse

http://lajeunesse.myweb.usf.edu/metagear/metagear_basic_vignette.html#introduction

“The metagear package for R contains tools for facilitating systematic reviews, data extraction, and meta-analyses.”

Any

Online documentation and the developer is available for questions. Requires knowledge of R in order to run the software although there is a GUI interface for abstract screening

Sc, Co, Sy

No

Yes

Yes, package operates offline

Yes

“PDF downloader to automate the retrieval of journal articles from online data bases; automated data extractions from scatter-plots, box-plots and bar-plots”

Yes

Free

PARSIFAL

Parsifal is a non-profit organisation

https://parsif.al/

“Parsifal is an online tool designed to support researchers to perform systematic literature reviews within the context of Software Engineering.”

Software engineering

FAQs, online videos, Github repository (https://github.com/vitorfs/parsifal) and email support available

Pi, Se, Du, Sc, Co, Sy

Yes

No

No

Yes

No

Yes

Free

Rayyan [40]

Qatar Computing Research Institute

https://rayyan.qcri.org

“Authors create systematic reviews, collaborate on them, maintain them over time and get suggestions for article inclusion.”

Any, close alignment with Cochrane reviews

Online forum

Pi, Se, Du, Sc

Yes

No

Yes, using a mobile app

Yes

The support vector machine classifier learns from users’ decisions about including and excluding studies and scores unclassified studies for likely relevance. Similarity graph function for exploring citation networks

No

Free

REviewER

Empirical Software Engineering Group

https://sites.google.com/site/eseportal/tools/reviewer

“REviewER aims at assisting researchers in the laborious process of conduction of systematic reviews.”

Any, particularly software engineering.

GitHub repository (https://github.com/bfsc/reviewer). No user guide. Advanced coding skills required

Qu, Pi, Se, Du, Sc

No

Yes

Yes, package operates offline

Yes

No

Yes

Free

RevMan 5 [41] (this software is no longer being developed)

Cochrane Community

http://community.cochrane.org/tools/review-production-tools/revman-5

“Review Manager 5 (RevMan 5) is the software used for preparing and maintaining Cochrane Reviews.”

Healthcare and medical science, designed for Cochrane reviews

Online documentation. RevMan 5 support accounts are only available to registered Cochrane authors

Pi, Sc, Co, Cr, Sy, Do d

No

Yes

Yes, package operates offline

Yes (cannot edit simultaneously)

No

No

RevMan 5 is free for Cochrane Reviewers or purely academic use. Commercial users require a license

RevMan Web (will be available for beta-testing in 2017, building on RevMan 5)

Cochrane Community

http://community.cochrane.org/tools/review-production-tools/revman-web

“RevMan Web is a new, web-based platform for preparing and maintaining Cochrane Reviews.”

Healthcare and medical science, designed for Cochrane reviews

RevMan Web will integrate with several other Cochrane software packages

Unavailable

Yes

Unavailable

Unavailable

Unavailable

Unavailable

Unavailable

Unavailable

SESRA (supporting systematic literature reviews in software engineering) [29]

UNIVALI—Universidade do Vale do Itajaí

http://sesra.net/

“Collaborative research, automated searches, online reference management, support to all the process phases and activities.”

Any, particularly designed for software engineering

User guide and introductory videos available in Portuguese only

Qu, Pi, Sc, Co, Sy, Do

Yes

No

No

Yes

No

Proposed in future

Free

SLR-tool [42]

ALARCOS Research Group

http://alarcos.esi.uclm.es/slrtool/

“…a free tool… to be used by researchers from any discipline, and not only Software Engineering.”

Any, particularly designed for software engineering

Unavailable

Qu, Pi, Du, Sc, Co, Cr, Do

No

Yes

Yes, package operates offline

No

Yes, for example “…to cluster the documents by using the similarities among them, highlighting key words that identify each group of documents.”

No

Free

SLuRp (systematic literature unified Review program) [43]

See authors

https://codefeedback.cs.herts.ac.uk/SLuRp/

“…to support the complex task of managing large numbers of papers, sharing tasks amongst a research team and following the arduous and rigorous SLR methodology recommended by Kitchenham and Charters.”

Software engineering

No user guide, minimal support information on product website. Requires use of MySql and Tomcat to run

Se, Sc, Co, Cr, Sy, Do

Partially

Unavailable

Unavailable

Yes

No

Yes

Free

SRDB.PRO—systematic review intelligence Platform

Privately held

https://www.srdb.pro/default

“…the first, enterprise level Business Intelligence platform designed specifically to improve the way in which the pharmaceutical industry and healthcare consultancies conduct systematic reviews and data analysis.”

Healthcare and medical science, targeting the pharmaceutical industry and healthcare consultancies

User guide. Phone and email support

Se (PubMed), Du, Sc, Co, Cr, Sy, Do

No

Yes

Yes, package operates offline

Yes

No

No

SRDB.PRO Hosted is free for non-commercial use and starts at £70/USD$119 per month for 1 active user. SRDB.PRO Enterprise is more expensive

SRDR (systematic review data repository)

Brown Evidence-based Practice Center

http://srdr.ahrq.gov/

“…a Web-based tool for data extraction and storage of systematic review data.”

Healthcare and medical science

User manual, FAQs and training videos

Se, Co, Sy

Yes

No

No

Yes

No

No

Free

StArt (state of the art through systematic review) [44]

Laboratory of Research on Software Engineering (LaPES)

http://lapes.dc.ufscar.br/tools/start_tool

“…aims to help the researcher, giving support to the application of this technique [systematic review]”

Software engineering

The online StArt community provides a forum, tutorials and videos

Pi, Du, Sc, Co, Cr, Sy, Do

No

Yes

Yes, package operates offline

No

Yes, calculates scores of likely relevance of articles and similarity between articles

No

Free

SUMARI (system for the unified management, assessment and review of information). (designed to replace JBI CReMS software)

Joanna Briggs Institute (JBI)

https://www.jbisumari.org/

“SUMARI supports 10 review types, including reviews of effectiveness, qualitative research, economic evaluations, prevalence/incidence, aetiology/risk, mixed methods, umbrella/overviews, text/opinion, diagnostic test accuracy and scoping reviews.”

Healthcare and medical science, also social sciences and humanities

FAQs and video tutorials

Se, Sc (full text only), Co, Cr, Sy, Do

Yes

No

No

Yes

No

No

Limited access beyond JBI special users initially. Subscriptions will be made available via Wolters Kluwer

SWIFT-review (Sciome workbench for interactive computer-facilitated text-mining) [45]

Privately held, Sciome

https://www.sciome.com/swift-review/

“a freely available interactive workbench which provides numerous tools to assist with problem formulation and literature prioritization.”

Healthcare and medical science

Tutorial and user guide

Se (PubMed), Sc (works in concert with SWIFT-ACTIVE Screener), Co, Sy, Do

No

Yes

Yes, package operates offline

Yes

Yes, the “software utilizes recently developed statistical modeling and machine learning methods that allow users to identify over-represented topics within the literature corpus and to rank-order titles and abstracts for manual screening.”

No

Free

SyRF (systematic review and meta-analysis facility) [46]

CAMARADES and NC3Rs

http://syrf.org.uk/

“SyRF is a fully integrated online platform for performing systematic reviews of preclinical studies.”

Preclinical studies e.g. experimental animal studies

Online contact form, online tutorials available on request. User guide, video tutorial and in app tutorials in development

Qu, Pi, Se (PubMed), Sc, Co, Cr, Sy

Yes

No (under development)

No (offline app under development)

Yes

Risk of bias items can be automatically extracted and machine learning is available to aid the screening process for English articles

No

Free

  1. aDescriptions taken from product websites, referenced documentation or through direct email contact with developers (where necessary)
  2. bStages of a systematic review: Qu setting up the review, with question formulation and/or stakeholder engagement, Pi scoping/pilot study, protocol development (e.g. PICO elements specified), Se literature searching (e.g. via integration with publication databases). Excludes those which require search results to be manually uploaded, Du duplicate checking (e.g. automated marking of duplicates, or identification of potential duplicates for manual checking), Sc article screening/study selection, Co facilitates data coding/tagging and extraction to support meta-analyses, Cr critical appraisal/risk of bias assessments, Sy facilitates quantitative/qualitative syntheses of results, Do generation of documentation/output of text, figures or tables to assist with report writing
  3. cCosts taken from respective websites, correct as of 02/11/2017. EROS cost estimates were provided by email (Gabriela Rodriguez, 07/04/17)