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Table 2 Key features of CADIMA, different user roles and associated tasks and supported information formats used during the synthesis process

From: Online tools supporting the conduct and reporting of systematic reviews and systematic maps: a case study on CADIMA and review of existing tools

Step Key features of CADIMA Roles and tasks Information format
Set up the review Predefined input structure RC
Invite registered users to become part of the review team
Define the title of the review
Define the question type (PICO, PIT, PO)
Define if a systematic review or a systematic map will be performed
Manual entry
Protocol Predefined input structure referring to the key chapters of a protocol
Compile a drafted protocol document with potential annexes
Mark those document blocks that should be compiled by CADIMA
Make final protocol publically available
Enter/upload the requested information
Manual entry
Upload/download formats:
- Docx
- Xlsx
- Pdf
Literature search Documentation of the literature search
Indication of reports with missing abstract
Identification of duplicates
Allocate a search string to a search engine or a further information source it was applied
Upload of search results and duplicate removal
Manual entry
Upload/download formats:
Study selection Support for the:
 Definition of selection criteria
 Performance of a kappa-test
- Takes a random sample of the identified reports to be rated by RC and/or further review team members
- Kappa value will be provided
 Online application of selection criteria
- Title/abstract/full text will be co-displayed
- Identification of discrepancies in the rating by RC and/or RM
 Selection of studies that should be included in the review
Set the criteria list as “final”
Define those team members that should be involved in the kappa test
Decide about the suitability of the criteria based on the provided kappa value
Nominate team members to be involved during study selection
- Decide about the application mode
- Allocate identified reports
Enter selection criteria
If nominated, apply criteria
Extract relevant studies
Manual entry
Data extraction On- and offline data extraction All
Define critical appraisal criteria
Define data extraction columns
Mark those columns relevant for the critical appraisal
Perform data extraction
Manual entry
Online data extraction
- Manual entry
Offline data extraction
- Download/upload of the data extraction sheet as excel file
Critical appraisal Co-display of extracted (meta-) data during the rating process
Online application of appraisal criteria
Identification of inconsistencies in reviewer judgments
Nominate team members to be involved during critical appraisal
 Allocate relevant studies
If nominated, critically appraise included studies
Manual entry
Data synthesis Compilation of the data extraction sheet and the results from the critical appraisal All
Perform the statistical analysis by using the software package of their choice
Upload of synthesis results
Download format
-  Xlsx
Upload formats:
- Xlsx
- Docx
- Pdf
Presenting data and results Thorough documentation (including any decision made during) of
- Literature search
- Study selection
- Critical appraisal
Compilation of data extraction sheet
Opt for publication on the web site
Write up the review
Decide about and upload information to be made publically available
Download formats:
- Xlsx
- Docx
Upload formats:
- Xlsx
- Docx
-  Pdf
  1. This table illustrates the key features of CADIMA for each step within the evidence synthesis process, describes the different user roles and associated tasks (RC review coordinator, All the entire review team), and specifies the information formats supported for each step. For more detail see text