How effective are strategies to control the dissemination of antibiotic resistance in the environment? A systematic review

Table 8 Most frequently measured ARGs (N ≥ 10 articles) in organic waste and number of articles (N) in which they are measured (among the 98 articles preselected for the meta-analysis)

ARG	Antibiotic family targeted	Mechanism of resistance^a	N articles
sul1	Sulfonamide	Target replacement	48
sul2	Sulfonamide	Target replacement	42
tetX	Tetracycline	Antibiotic inactivation	41
tetW	Tetracycline	Target protection	40
tetM	Tetracycline	Target protection	36
ermB	Macrolide	Target alteration	35
tetO	Tetracycline	Target protection	29
ermF	Macrolide	Target alteration	27
tetG	Tetracycline	Antibiotic efflux	26
tetC	Tetracycline	Antibiotic efflux	25
tetQ	Tetracycline	Target protection	23
tetA	Tetracycline	Antibiotic efflux	21
ermX	Macrolide	Target alteration	14
tetB	Tetracycline	Antibiotic efflux	13
tetL	Tetracycline	Antibiotic efflux	13

All ATBR markers measured in these articles are available in Additional file 7. Data issued from the dataset for meta-analysis on organic waste treatments (Additional file 6)
^aResistance mechanisms were obtained from The Comprehensive Antibiotic Resistance Database (https://card.mcmaster.ca/)

ISSN: 2047-2382